Medical history is vitally important for any medical treatment. This includes non-surgical cosmetic treatments such as botulinum toxin (Botox, Azzalure, Bocouture) injections, dermal fillers (Restylane, Juvederm, Belotero, Radiesse), thread lifts (Silhouette Soft, PDO) and many other treatments which are currently being treated as beauty treatments, but they are not. A history of previous side effects [...]

It is unfortunate that we are seeing more patients who have had treatment with botox without proper consultation and sometimes even for the wrong indication. For instance there have been patients who developed double vision following botox injection but continued to have the area of treatment that was causing this side effect. At Reverse Time [...]

Generally, if the patient is aged over 18 years and presents with a reasonable indication that will benefit from treatment with botulinum toxin such as Botox. There are a few restrictions, such as for pregnant or breastfeeding women. The effect of botulinum on these patient groups is un-tested. It would be unethical to offer Botox [...]

There have been no reported cases of true allergic reaction to Botox. This is based on the existing literature.

There are some reasons why Botox may not produce the expected results in some patients. One interesting cause is that of developing resistance to Botox®: This is possible if you develop antibodies against the toxin. Higher doses (not in cosmetic treatments) and too frequent treatments can increase this risk. There are possible solutions to resistance. [...]

We are often asked by patients if they will get worse lines than before if they discontinue treatments with Botox. We can strongly reassure them that this is not the case. If you do not continue treatments with Botox®, the areas which you had treated will gradually look like they did before treatment.

This is not entirely true. Some patients have overactive or "hyperdynamic" muscles, particularly the frown muscles causing vertical frown lines. If they do not relax these muscles, they will ultimately develop "static" lines which cannot be completely treated with Botox. These patients, if treated with Botox before they form static lines, will have effectively prevented [...]

This answer is assuming that the question refers to the wrinkle relaxing effect of Botox in facial treatment, such as frown lines. The maximum effect is reached in about 2 weeks. Your facial expression will become more relaxed but by no means mask like. The overall effect is very natural if a well balanced treatment [...]

The original question was "Will getting Botox on the outer corner of the eye that wrinkles when smiling, change the look of your expression when smiling?" This question is not only about Botox treatment, but about the science and philosophy of expression and emotion. On the surface it may seem the right thing to do [...]

The first 2 weeks are crucial to botulinum toxin treatment producing a satisfactory outcome. Immediately after treatment, the needle marks may be visible. These will fade over the next day. There is no downtime. Visible results become noticed in 10-14 days after Botox treatment.