When the Moderna vaccine was undergoing clinical trials, two people developed facial swelling after vaccination. Both patients had had dermal fillers injected into their face (cheeks) at different times before they received the vaccine.

One of them had the filler injection a fortnight before the vaccine, and the other had fillers injected about six months before.

A third trial participant had swelling in her lips after the Moderna vaccine. It turned out that she had a history of lip filler treatments (when she had the lip filler injection, or how long before the vaccine, is unclear).

Interestingly, there were reports of a similar response (lip swelling) after receiving the flu jab.